Corydalis yanhusuo and 13-OH
Corydalis yanhusuo is a plant in the poppy family whose rhizome contains a range of isoquinoline alkaloids, the best characterized of which is tetrahydropalmatine (THP), molecular formula C21H25NO4. The market term 13-OH refers to a hydroxylated alkaloid derived from this plant and related to that scaffold.
Unlike mitragynine and speciociliatine, whose structures are well documented, the precise structure of the commercial 13-OH is not yet established in the public literature. We describe it by its source and scaffold, and confirm each lot by analysis rather than by name alone.
What is Corydalis yanhusuo?
Corydalis yanhusuo is a flowering plant in the family Papaveraceae, the poppy family, native to East Asia. Its rhizome contains a complex mixture of isoquinoline alkaloids.
What is tetrahydropalmatine (THP)?
Tetrahydropalmatine is a tetrahydroprotoberberine isoquinoline alkaloid with the molecular formula C21H25NO4 that occurs naturally in Corydalis yanhusuo and related plants. Its levorotatory form is commonly written l-THP.
What is 13-OH?
In the current market, 13-OH refers to a hydroxylated alkaloid derived from Corydalis yanhusuo, related to the tetrahydroprotoberberine scaffold. Its precise structure is not yet established in the public scientific literature, so we describe it by its source and scaffold rather than a fixed identity.
Is 13-OH the same as 7-OH?
No. 7-OH (7-hydroxymitragynine) is an indole alkaloid associated with Mitragyna speciosa, the kratom plant. 13-OH refers to a Corydalis yanhusuo derived alkaloid in the isoquinoline family, a different plant and a different chemical class. The similar names are a common source of confusion.
In tablet form
We use a Corydalis-derived 13-OH alkaloid in blend tablets alongside a standardized kratom alkaloid. Each lot is third-party tested, manufactured in the USA, and available for bulk supply and co-packing.
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This page describes chemical structure and natural occurrence only.