MitraGen

Speciociliatine

Speciociliatine is a monoterpenoid indole alkaloid and a diastereomer of mitragynine, sharing the molecular formula C23H30N2O4, that occurs naturally as a minor alkaloid in the leaves of Mitragyna speciosa.

Molecular formula
C23H30N2O4
Systematic name
Pending verification
Natural abundance
Minor

What is Speciociliatine?

Speciociliatine is a monoterpenoid indole alkaloid and a diastereomer of mitragynine, sharing the molecular formula C23H30N2O4, that occurs naturally as a minor alkaloid in the leaves of Mitragyna speciosa.

Where does Speciociliatine occur naturally?

Speciociliatine occurs in the leaves of Mitragyna speciosa (kratom), typically as one of the minor alkaloids within the leaf alkaloid fraction.

How is Speciociliatine related to mitragynine?

Speciociliatine and mitragynine are both monoterpenoid indole alkaloids from Mitragyna speciosa that share the same indole scaffold; Speciociliatine has the molecular formula C23H30N2O4 and mitragynine has the molecular formula C23H30N2O4.

Structure and chemistry

Speciociliatine shares the indole and quinolizidine framework of mitragynine and differs from it in stereochemistry at the C-3 position, making it a corynanthe-type diastereomer.

Because it is a stereoisomer of mitragynine, it has the identical molecular formula and closely related structural features, and it is distinguished analytically by chromatographic separation.

Speciociliatine compared with related alkaloids

Comparison of Speciociliatine with related Mitragyna alkaloids by molecular formula, systematic name, and natural abundance
AlkaloidMolecular formulaSystematic name (IUPAC)Natural abundance
SpeciociliatineC23H30N2O4Pending verificationMinor
MitragynineC23H30N2O4Pending verificationPredominant
PaynantheineC23H28N2O4Pending verificationSecond most abundant
SpeciogynineC23H30N2O4Pending verificationMinor

Sources

  1. Analytical separation of Mitragyna speciosa diastereomeric indole alkaloids (review)

Reviewed for scientific accuracy on 2026-07-15. This entry describes chemical structure and natural occurrence only.