Speciogynine

What is Speciogynine?

Speciogynine is a monoterpenoid indole alkaloid and a diastereomer of mitragynine, sharing the molecular formula C23H30N2O4, that occurs naturally as a minor alkaloid in the leaves of Mitragyna speciosa.

Where does Speciogynine occur naturally?

Speciogynine occurs in the leaves of Mitragyna speciosa (kratom), typically as one of the minor alkaloids within the leaf alkaloid fraction.

What is the molecular formula of Speciogynine?

Speciogynine has the molecular formula C23H30N2O4.

Is Speciogynine found in kratom?

Speciogynine is one of the naturally occurring alkaloids in the leaves of Mitragyna speciosa, the tree commonly known as kratom.

How is Speciogynine identified?

Speciogynine is identified and measured by chromatographic and spectroscopic analysis of the leaf alkaloid fraction, which resolves it from the other Mitragyna alkaloids.

How is Speciogynine related to mitragynine?

Speciogynine and mitragynine are both monoterpenoid indole alkaloids from Mitragyna speciosa that share the same indole scaffold; Speciogynine has the molecular formula C23H30N2O4 and mitragynine has the molecular formula C23H30N2O4.

Structure and chemistry

Speciogynine is a corynanthe-type diastereomer of mitragynine, differing in stereochemistry within the quinolizidine ring system while retaining the same indole nucleus and substituent pattern.

As a stereoisomer it carries the identical molecular formula to mitragynine and is distinguished from its relatives by chromatographic and spectroscopic analysis.

Speciogynine compared with related alkaloids

Related alkaloids

• Mitragynine
• Speciociliatine
• Paynantheine

Sources

1. [1]Structural characterization of minor indole alkaloids in Mitragyna speciosa (review)